1ZYQ

T7 DNA polymerase in complex with 8oG and incoming ddATP

Summary for 1ZYQ

• Entry DOI: 10.2210/pdb1zyq/pdb
• Related: 1T7P
• Descriptor: 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3', 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', DNA polymerase, ... (7 entities in total)
• Functional Keywords: 8og, fidelity, transferase-electron transport-dna complex, transferase/electron transport/dna
• Biological source: Enterobacteria phage T7; More
• Total number of polymer chains: 4
• Total formula weight: 105970.63

Authors

Brieba, L.G.,Kokoska, R.J.,Bebenek, K.,Kunkel, T.A.,Ellenberger, T. (deposition date: 2005-06-10, release date: 2005-11-22, Last modification date: 2024-02-14)

• Primary citation: Brieba, L.G.,Kokoska, R.J.,Bebenek, K.,Kunkel, T.A.,Ellenberger, T.; A lysine residue in the fingers subdomain of t7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.; Structure, 13:1653-1659, 2005; PubMed: 16271888; DOI: 10.1016/j.str.2005.07.020

Experimental method

X-RAY DIFFRACTION (2.7 Å)