1ZXN
Human DNA topoisomerase IIa ATPase/ADP
Summary for 1ZXN
Entry DOI | 10.2210/pdb1zxn/pdb |
Related | 1ZXM |
Descriptor | DNA topoisomerase II, alpha isozyme, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | ghkl nucleotide-binding fold, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P11388 |
Total number of polymer chains | 4 |
Total formula weight | 184732.38 |
Authors | Wei, H.,Ruthenburg, A.J.,Bechis, S.K.,Verdine, G.L. (deposition date: 2005-06-08, release date: 2005-08-23, Last modification date: 2024-02-14) |
Primary citation | Wei, H.,Ruthenburg, A.J.,Bechis, S.K.,Verdine, G.L. Nucleotide-dependent Domain Movement in the ATPase Domain of a Human Type IIA DNA Topoisomerase. J.Biol.Chem., 280:37041-37047, 2005 Cited by PubMed: 16100112DOI: 10.1074/jbc.M506520200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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