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1ZXN

Human DNA topoisomerase IIa ATPase/ADP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
DNA topoisomerase II, alpha isozymepolymer40045660.54UniProt (P11388)
Pfam (PF02518)
Pfam (PF00204)
Homo sapiens (human)topo IIa ATPase
2E, H, K, M
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3F, J, L, O
(A, B, C, D)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.24Chemie (ADP)
4G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5I, N
(B, D)
SULFATE IONnon-polymer96.12Chemie (SO4)
6P, Q, R, S
(A, B, C, D)
waterwater18.0238Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight182642.1
Non-Polymers*Number of molecules11
Total formula weight2090.2
All*Total formula weight184732.4
*Water molecules are not included.

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PDB entries from 2026-01-28

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