1ZX1

Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954

Summary for 1ZX1

• Entry DOI: 10.2210/pdb1zx1/pdb
• Related: 1QR1 1QR2
• Descriptor: NRH dehydrogenase [quinone] 2, ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: quinone oxidoreductase 2, reductions of quinones, dihydronicotinamide ribose, electrondonor, 5-(aziridin-1-yl)-2, 4-dinitrobenamide (cb1954), flavin-containing, structural genomics, structural genomics consortium, sgc, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 54167.35

Authors

Jansson, A.,Wu, X.,Kavanagh, K.,Kerr, D.,Knox, R.,Walton, R.,Gunther, U.,Ludwig, C.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-06-06, release date: 2005-06-14, Last modification date: 2023-08-23)

• Primary citation: Jansson, A.,Wu, X.,Kavanagh, K.,Kerr, D.,Knox, R.,Walton, R.,Gunther, U.,Ludwig, C.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,von Delft, F.,Oppermann, U.; Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954; To be Published,

Experimental method

X-RAY DIFFRACTION (2.16 Å)