1ZW0

Crystal structure of the Yersinia Type III Secretion protein YscE

Summary for 1ZW0

Entry DOI	10.2210/pdb1zw0/pdb
Descriptor	type III secretion protein (2 entities in total)
Functional Keywords	type iii secretion, chaperone, yersinia, translocation, export
Biological source	Yersinia pestis
Total number of polymer chains	8
Total formula weight	60934.84
Authors	Phan, J.,Austin, B.P.,Waugh, D.S. (deposition date: 2005-06-03, release date: 2005-08-23, Last modification date: 2024-02-14)
Primary citation	Phan, J.,Austin, B.P.,Waugh, D.S. Crystal structure of the Yersinia type III secretion protein YscE Protein Sci., 14:2759-2763, 2005 Cited by PubMed Abstract: The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed. PubMed: 16195558 DOI: 10.1110/ps.051706105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation