1ZVR

Crystal Structure of MTMR2 in complex with phosphatidylinositol 3,5-bisphosphate

Summary for 1ZVR

• Entry DOI: 10.2210/pdb1zvr/pdb
• Related: 1ZSQ
• Descriptor: Myotubularin-related protein 2, 1,2-ETHANEDIOL, (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE, ... (4 entities in total)
• Functional Keywords: protein-phosphoinositide complex, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q13614
• Total number of polymer chains: 1
• Total formula weight: 61926.98

Authors

Begley, M.J.,Taylor, G.S.,Brock, M.A.,Ghosh, P.,Woods, V.L.,Dixon, J.E. (deposition date: 2005-06-02, release date: 2006-01-31, Last modification date: 2023-08-23)

• Primary citation: Begley, M.J.,Taylor, G.S.,Brock, M.A.,Ghosh, P.,Woods, V.L.,Dixon, J.E.; Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase; Proc.Natl.Acad.Sci.Usa, 103:927-932, 2006; PubMed: 16410353; DOI: 10.1073/pnas.0510006103

Experimental method

X-RAY DIFFRACTION (1.98 Å)