2FXK

Crystal structure of the macro-domain of human core histone variant macroH2A1.1 (form A)

Replaces:  1ZQ0

Summary for 2FXK

• Entry DOI: 10.2210/pdb2fxk/pdb
• Related: 1zr3 1zr5
• Descriptor: H2A histone family, member Y isoform 1 (2 entities in total)
• Functional Keywords: chromatin, histone, a1pp, macro-domain, p-loop, gene regulation
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 44548.67

Authors

Kustatscher, G.,Hothorn, M.,Pugieux, C.,Scheffzek, K.,Ladurner, A.G. (deposition date: 2006-02-06, release date: 2006-02-14, Last modification date: 2023-08-30)

• Primary citation: Kustatscher, G.,Hothorn, M.,Pugieux, C.,Scheffzek, K.,Ladurner, A.G.; Splicing regulates NAD metabolite binding to histone macroH2A.; Nat.Struct.Mol.Biol., 12:624-625, 2005; PubMed: 15965484; DOI: 10.1038/nsmb956

Experimental method

X-RAY DIFFRACTION (2.54 Å)