1ZPA
HIV Protease with Scripps AB-3 Inhibitor
Summary for 1ZPA
Entry DOI | 10.2210/pdb1zpa/pdb |
Related | 1ZP8 |
Descriptor | Pol polyprotein, TERT-BUTYL 4-[({[1-((1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}AMINO)CARBONYL]BENZYLCARBAMATE (3 entities in total) |
Functional Keywords | protease, retroviral, hydrolase |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 11525.69 |
Authors | Brik, A.,Alexandratos, J.,Lin, Y.C.,Elder, J.H.,Olson, A.J.,Wlodawer, A.,Goodsell, D.S.,Wong, C.H. (deposition date: 2005-05-16, release date: 2005-05-31, Last modification date: 2024-04-03) |
Primary citation | Brik, A.,Alexandratos, J.,Lin, Y.C.,Elder, J.H.,Olson, A.J.,Wlodawer, A.,Goodsell, D.S.,Wong, C.H. 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors Chembiochem, 6:1167-1169, 2005 Cited by PubMed: 15934050DOI: 10.1002/cbic.200500101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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