1ZHS

Crystal structure of MVL bound to Man3GlcNAc2

Summary for 1ZHS

• Entry DOI: 10.2210/pdb1zhs/pdb
• Related: 1ZHQ
• Descriptor: mannan-binding lectin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: mvl, hiv-1, carbohydrate binding, sugar binding protein
• Biological source: Microcystis viridis
• Total number of polymer chains: 8
• Total formula weight: 114334.18

Authors

Williams, D.C.,Lee, J.Y.,Cai, M.,Bewley, C.A.,Clore, G.M. (deposition date: 2005-04-26, release date: 2005-06-07, Last modification date: 2024-02-14)

• Primary citation: Williams, D.C.,Lee, J.Y.,Cai, M.,Bewley, C.A.,Clore, G.M.; Crystal Structures of the HIV-1 Inhibitory Cyanobacterial Protein MVL Free and Bound to Man3GlcNAc2: STRUCTURAL BASIS FOR SPECIFICITY AND HIGH-AFFINITY BINDING TO THE CORE PENTASACCHARIDE FROM N-LINKED OLIGOMANNOSIDE.; J.Biol.Chem., 280:29269-29276, 2005; PubMed: 15937331; DOI: 10.1074/jbc.M504642200

Experimental method

X-RAY DIFFRACTION (1.8 Å)