1ZGL

Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a

Summary for 1ZGL

Related1U3H 1FYT
DescriptorHLA class II histocompatibility antigen, DR alpha chain, major histocompatibility complex, class II, DR beta 5, Myelin basic protein, ... (5 entities in total)
Functional Keywordstcr-peptide-mhc complex, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Single-pass type I membrane protein P01903
Membrane ; Single-pass membrane protein  P01848 P01850
Total number of polymer chains20
Total molecular weight383726.25
Authors
Li, Y.,Huang, Y.,Lue, J.,Quandt, J.A.,Martin, R.,Mariuzza, R.A. (deposition date: 2005-04-21, release date: 2005-10-18, Last modification date: 2017-10-11)
Primary citation
Li, Y.,Huang, Y.,Lue, J.,Quandt, J.A.,Martin, R.,Mariuzza, R.A.
Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.
Embo J., 24:2968-2979, 2005
PubMed: 16079912 (PDB entries with the same primary citation)
DOI: 10.1038/sj.emboj.7600771
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2825411.5%11.7%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution