1Z4U

hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585

Summary for 1Z4U

Entry DOI	10.2210/pdb1z4u/pdb
Related	1YVF
Descriptor	HCV NS5B POLYMERASE, CHLORIDE ION, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	ns5b, polymerase, hcv, fingers, palm, thumb, transferase
Biological source	Hepatitis C virus
Total number of polymer chains	1
Total formula weight	65287.17
Authors	Pfefferkorn, J.A.,Greene, M.,Nugent, R.,Gross, R.J.,Mitchell, M.A.,Finzel, B.C.,Harris, M.S.,Wells, P.A.,Shelly, J.A.,Anstadt, R. (deposition date: 2005-03-16, release date: 2005-06-07, Last modification date: 2024-04-03)
Primary citation	Pfefferkorn, J.A.,Nugent, R.,Gross, R.J.,Greene, M.,Mitchell, M.A.,Reding, M.T.,Funk, L.A.,Anderson, R.,Wells, P.A.,Shelly, J.A.,Anstadt, R.,Finzel, B.C.,Harris, M.S.,Kilkuskie, R.E.,Kopta, L.A.,Schwende, F.J. Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid Bioorg.Med.Chem.Lett., 15:2812-2818, 2005 Cited by PubMed: 15911260 DOI: 10.1016/j.bmcl.2005.03.106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation