1Z4S

Crystal Structure of Gly19 and Glu60 deletion mutant of Human Acidic Fibroblast Growth Factor

Summary for 1Z4S

• Entry DOI: 10.2210/pdb1z4s/pdb
• Related: 1JQZ
• Descriptor: Heparin-binding growth factor 1, SULFATE ION (3 entities in total)
• Functional Keywords: beta-trefoil, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05230
• Total number of polymer chains: 4
• Total formula weight: 66194.45

Authors

Lee, J.,Blaber, M. (deposition date: 2005-03-16, release date: 2006-02-07, Last modification date: 2023-08-23)

• Primary citation: Lee, J.,Dubey, V.K.,Somasundaram, T.,Blaber, M.; Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.; Proteins, 62:686-697, 2005; PubMed: 16355415; DOI: 10.1002/prot.20808

Experimental method

X-RAY DIFFRACTION (2.6 Å)