1Z4Q

Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with 2',3'-dideoxy-2',3-didehydrothymidine 5'-monophosphate (d4T-MP)

1Z4Q の概要

• エントリーDOI: 10.2210/pdb1z4q/pdb
• 関連するPDBエントリー: 1Z4I 1Z4J 1Z4K 1Z4L 1Z4M 1Z4P
• 分子名称: 5'(3')-deoxyribonucleotidase, MAGNESIUM ION, [(5R)-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-2,5-DIHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: alfa beta fold, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion: Q9NPB1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23192.94

構造登録者

Wallden, K.,Ruzzenente, B.,Rinaldo-Matthis, A.,Bianchi, V.,Nordlund, P. (登録日: 2005-03-16, 公開日: 2005-07-26, 最終更新日: 2024-05-29)

• 主引用文献: Wallden, K.,Ruzzenente, B.,Rinaldo-Matthis, A.,Bianchi, V.,Nordlund, P.; Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase; STRUCTURE, 13:1081-1088, 2005; PubMed: 16004879; DOI: 10.1016/j.str.2005.04.023

実験手法

X-RAY DIFFRACTION (2.05 Å)