1Z1M

NMR structure of unliganded MDM2

Summary for 1Z1M

• Entry DOI: 10.2210/pdb1z1m/pdb
• NMR Information: BMRB: 6612
• Descriptor: Ubiquitin-protein ligase E3 Mdm2 (1 entity in total)
• Functional Keywords: peptide-binding groove, psudosymmetry, alpha-beta domains, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus, nucleoplasm: Q00987
• Total number of polymer chains: 1
• Total formula weight: 13571.59

Authors

Uhrinova, S.,Uhrin, D.,Powers, H.,Watt, K.,Zheleva, D.,Fischer, P.,McInnes, C.,Barlow, P.N. (deposition date: 2005-03-04, release date: 2005-06-28, Last modification date: 2022-03-02)

• Primary citation: Uhrinova, S.,Uhrin, D.,Powers, H.,Watt, K.,Zheleva, D.,Fischer, P.,McInnes, C.,Barlow, P.N.; Structure of Free MDM2 N-terminal Domain Reveals Conformational Adjustments that Accompany p53-binding; J.Mol.Biol., 350:587-598, 2005; PubMed: 15953616; DOI: 10.1016/j.jmb.2005.05.010

Experimental method

SOLUTION NMR