1YXU

Crystal Structure of Kinase Pim1 in Complex with AMP

Summary for 1YXU

Related1YWV 1YXT 1YXS 1YXX 1YXV
DescriptorProto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, ADENOSINE MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordsser/thr protein kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationIsoform 2: Cytoplasm. Isoform 1: Cell membrane P11309
Total number of polymer chains4
Total molecular weight136994.5
Authors
Kumar, A.,Mandiyan, V.,Suzuki, Y.,Zhang, C.,Rice, J.,Tsai, J.,Artis, D.R.,Ibrahim, P.,Bremer, R. (deposition date: 2005-02-22, release date: 2005-04-26, Last modification date: 2011-07-13)
Primary citation
Kumar, A.,Mandiyan, V.,Suzuki, Y.,Zhang, C.,Rice, J.,Tsai, J.,Artis, D.R.,Ibrahim, P.,Bremer, R.
Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348:183-193, 2005
PubMed: 15808862 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2005.02.039
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.24 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.28180.2%6.1%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1yxu
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Molmil generated image of 1yxu
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Molmil generated image of 1yxu
rotated about y axis by 90°