1YXK

Crystal structure of human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) disulfide-linked dimer

Summary for 1YXK

• Entry DOI: 10.2210/pdb1yxk/pdb
• Related: 1YXJ
• Descriptor: oxidised low density lipoprotein (lectin-like) receptor 1 (2 entities in total)
• Functional Keywords: c-type lectin-like domain, lox-1, ctld, scavenger receptor, oxidized ldl receptor, nk cell receptor, lipid binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type II membrane protein: P78380
• Total number of polymer chains: 2
• Total formula weight: 30624.77

Authors

Ohki, I.,Ishigaki, T.,Oyama, T.,Matsunaga, S.,Xie, Q.,Ohnishi-Kameyama, M.,Murata, T.,Tsuchiya, D.,Machida, S.,Morikawa, K.,Tate, S. (deposition date: 2005-02-22, release date: 2005-06-14, Last modification date: 2023-10-25)

• Primary citation: Ohki, I.,Ishigaki, T.,Oyama, T.,Matsunaga, S.,Xie, Q.,Ohnishi-Kameyama, M.,Murata, T.,Tsuchiya, D.,Machida, S.,Morikawa, K.,Tate, S.; Crystal structure of human lectin-like, oxidized low-density lipoprotein receptor 1 ligand binding domain and its ligand recognition mode to OxLDL.; Structure, 13:905-917, 2005; PubMed: 15939022; DOI: 10.1016/j.str.2005.03.016

Experimental method

X-RAY DIFFRACTION (2.4 Å)