1YVH

Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide

1YVH の概要

• エントリーDOI: 10.2210/pdb1yvh/pdb
• 分子名称: CBL E3 ubiquitin protein ligase, 13-mer fragment of SH2 and PH domain-containing adapter protein APS, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: x-ray crystallography; phosphotyrosine; adapter protein, ligase, signaling protein, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P22681 Q9Z200
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39859.06

構造登録者

Hu, J.,Hubbard, S.R. (登録日: 2005-02-15, 公開日: 2005-03-08, 最終更新日: 2023-11-15)

• 主引用文献: Hu, J.,Hubbard, S.R.; Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins; J.Biol.Chem., 280:18943-18949, 2005; PubMed: 15737992; DOI: 10.1074/jbc.M414157200

実験手法

X-RAY DIFFRACTION (2.05 Å)