1YQ4
Avian respiratory complex ii with 3-nitropropionate and ubiquinone
Summary for 1YQ4
Entry DOI | 10.2210/pdb1yq4/pdb |
Related | 1YQ3 |
Descriptor | Succinate dehydrogenase flavoprotein subunit, GLYCEROL, hexyl beta-D-glucopyranoside, ... (15 entities in total) |
Functional Keywords | complex ii, membrane protein, heme protein, iron sulfur protein, cytochrome b, oxidoreductase, redox enzyme, respiratory chain, oxaloacetate nitropropionate ubiquinone |
Biological source | Gallus gallus (chicken) More |
Total number of polymer chains | 4 |
Total formula weight | 128409.16 |
Authors | Huang, L.,Sun, G.,Cobessi, D.,Wang, A.,Shen, J.T.,Tung, E.Y.,Anderson, V.E.,Berry, E.A. (deposition date: 2005-02-01, release date: 2005-12-20, Last modification date: 2020-07-29) |
Primary citation | Huang, L.,Sun, G.,Cobessi, D.,Wang, A.C.,Shen, J.T.,Tung, E.Y.,Anderson, V.E.,Berry, E.A. 3-Nitropropionic Acid Is a Suicide Inhibitor of Mitochondrial Respiration That, upon Oxidation by Complex II, Forms a Covalent Adduct with a Catalytic Base Arginine in the Active Site of the Enzyme J.Biol.Chem., 281:5965-5972, 2006 Cited by PubMed: 16371358DOI: 10.1074/jbc.M511270200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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