1YLA
Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2)
Summary for 1YLA
Entry DOI | 10.2210/pdb1yla/pdb |
Descriptor | Ubiquitin-conjugating enzyme E2-25 kDa (2 entities in total) |
Functional Keywords | ubiquitin, ubiquitin- conjugating enzyme, ligase, structural genomics, sgc, structural genomics consortium |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): P61086 |
Total number of polymer chains | 2 |
Total formula weight | 45149.44 |
Authors | Choe, J.,Avvakumov, G.V.,Newman, E.M.,Mackenzie, F.,Kozieradzki, I.,Bochkarev, A.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Dhe-paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-01-19, release date: 2005-02-01, Last modification date: 2023-08-23) |
Primary citation | Ko, S.,Kang, G.B.,Song, S.M.,Lee, J.-G.,Shin, D.Y.,Yun, J.-H.,Sheng, Y.,Cheong, C.,Jeon, Y.H.,Jung, Y.-K.,Arrowsmith, C.H.,Avvakumov, G.V.,Dhe-Paganon, S.,Yoo, Y.J.,Eom, S.H.,Lee, W. Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285:36070-36080, 2010 Cited by PubMed: 20826778DOI: 10.1074/jbc.M110.145219 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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