1YLA

Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2)

1YLA の概要

• エントリーDOI: 10.2210/pdb1yla/pdb
• 分子名称: Ubiquitin-conjugating enzyme E2-25 kDa (2 entities in total)
• 機能のキーワード: ubiquitin, ubiquitin- conjugating enzyme, ligase, structural genomics, sgc, structural genomics consortium
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (By similarity): P61086
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 45149.44

構造登録者

Choe, J.,Avvakumov, G.V.,Newman, E.M.,Mackenzie, F.,Kozieradzki, I.,Bochkarev, A.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Dhe-paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2005-01-19, 公開日: 2005-02-01, 最終更新日: 2023-08-23)

• 主引用文献: Ko, S.,Kang, G.B.,Song, S.M.,Lee, J.-G.,Shin, D.Y.,Yun, J.-H.,Sheng, Y.,Cheong, C.,Jeon, Y.H.,Jung, Y.-K.,Arrowsmith, C.H.,Avvakumov, G.V.,Dhe-Paganon, S.,Yoo, Y.J.,Eom, S.H.,Lee, W.; Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity; J.Biol.Chem., 285:36070-36080, 2010; PubMed: 20826778; DOI: 10.1074/jbc.M110.145219

実験手法

X-RAY DIFFRACTION (2.4 Å)