1YE4
Crystal structure of the Lys-274 to Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+
Summary for 1YE4
Entry DOI | 10.2210/pdb1ye4/pdb |
Related | 1YE6 |
Descriptor | NAD(P)H-dependent D-xylose reductase, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | beta-alpha-barrel akr aldo-keto reductase coenzyme specificity nad, oxidoreductase |
Biological source | Candida tenuis |
Total number of polymer chains | 4 |
Total formula weight | 147590.94 |
Authors | Leitgeb, S.,Petschacher, B.,Wilson, D.K.,Nidetzky, B. (deposition date: 2004-12-28, release date: 2005-02-01, Last modification date: 2023-08-23) |
Primary citation | Leitgeb, S.,Petschacher, B.,Wilson, D.K.,Nidetzky, B. Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD(+) and NADP(+). FEBS Lett., 579:763-767, 2005 Cited by PubMed: 15670843DOI: 10.1016/j.febslet.2004.12.063 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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