1YDO

Crystal Structure of the Bacillis subtilis HMG-CoA Lyase, Northeast Structural Genomics Target SR181.

Summary for 1YDO

• Entry DOI: 10.2210/pdb1ydo/pdb
• Related: 1YDN
• Descriptor: HMG-CoA Lyase, IODIDE ION (3 entities in total)
• Functional Keywords: tim-barrel protein, structural genomics, psi, protein structure initiative, northeast structural genomics consortium, nesg, lyase
• Biological source: Bacillus subtilis subsp. subtilis
• Total number of polymer chains: 4
• Total formula weight: 136822.26

Authors

Forouhar, F.,Hussain, M.,Edstrom, W.,Vorobiev, S.M.,Xiao, R.,Ciano, M.,Shih, L.,Acton, T.B.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2004-12-24, release date: 2005-07-05, Last modification date: 2017-10-11)

• Primary citation: Forouhar, F.,Hussain, M.,Farid, R.,Benach, J.,Abashidze, M.,Edstrom, W.C.,Vorobiev, S.M.,Xiao, R.,Acton, T.B.,Fu, Z.,Kim, J.J.,Miziorko, H.M.,Montelione, G.T.,Hunt, J.F.; Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.; J.Biol.Chem., 281:7533-7545, 2006; PubMed: 16330546; DOI: 10.1074/jbc.M507996200

Experimental method

X-RAY DIFFRACTION (2.71 Å)