Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites

Summary for 1XXV

Related1XXP 1QZ0
DescriptorProtein-tyrosine phosphatase yopH, Epidermal growth factor receptor derived peptide (3 entities in total)
Functional Keywordscatalytic domain, phosphotyrosine-binding sites, substrate targeting, hydrolase
Biological sourceYersinia enterocolitica
Cellular locationSecreted P15273
Total number of polymer chains6
Total molecular weight70490.6
Ivanov, M.I.,Stuckey, J.A.,Schubert, H.L.,Saper, M.A.,Bliska, J.B. (deposition date: 2004-11-08, release date: 2005-03-22, Last modification date: 2011-09-14)
Primary citation
Ivanov, M.I.,Stuckey, J.A.,Schubert, H.L.,Saper, M.A.,Bliska, J.B.
Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Mol.Microbiol., 55:1346-1356, 2005
PubMed: 15720545 (PDB entries with the same primary citation)
DOI: 10.1111/j.1365-2958.2005.04477.x
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers90.7%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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