1XXV

Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites

Summary for 1XXV

Entry DOI	10.2210/pdb1xxv/pdb
Related	1QZ0 1XXP
Descriptor	Protein-tyrosine phosphatase yopH, Epidermal growth factor receptor derived peptide (3 entities in total)
Functional Keywords	catalytic domain, phosphotyrosine-binding sites, substrate targeting, hydrolase
Biological source	Yersinia enterocolitica More
Cellular location	Secreted: P15273
Total number of polymer chains	6
Total formula weight	70490.60
Authors	Ivanov, M.I.,Stuckey, J.A.,Schubert, H.L.,Saper, M.A.,Bliska, J.B. (deposition date: 2004-11-08, release date: 2005-03-22, Last modification date: 2024-04-03)
Primary citation	Ivanov, M.I.,Stuckey, J.A.,Schubert, H.L.,Saper, M.A.,Bliska, J.B. Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence Mol.Microbiol., 55:1346-1356, 2005 Cited by PubMed: 15720545 DOI: 10.1111/j.1365-2958.2005.04477.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation