1XWS

Crystal Structure of the human PIM1 kinase domain

Summary for 1XWS

• Entry DOI: 10.2210/pdb1xws/pdb
• Descriptor: Proto-oncogene serine/threonine-protein kinase Pim-1, SULFATE ION, 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, ... (4 entities in total)
• Functional Keywords: pim1, kinase, cancer, leukemia, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• Total number of polymer chains: 1
• Total formula weight: 36241.29

Authors

Knapp, S.,Debreczeni, J.,Bullock, A.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Guo, K. (deposition date: 2004-11-02, release date: 2004-11-16, Last modification date: 2024-03-13)

• Primary citation: Knapp, S.,Debreczeni, J.,Bullock, A.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Guo, K.; Crystal structure of human PIM1 kinase domain; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)