1XUI
TRYPSIN-KETO-BABIM, ZN+2-FREE, PH 8.2
Summary for 1XUI
Entry DOI | 10.2210/pdb1xui/pdb |
Descriptor | TRYPSIN, CALCIUM ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | complex, trypsin-small molecule ligand, designed small molecule ligand with micromolar affinity, serine protease |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 23733.70 |
Authors | Katz, B.A.,Clark, J.M.,Finer-Moore, J.S.,Jenkins, T.E.,Johnson, C.R.,Rose, M.J.,Luong, C.,Moore, W.R.,Stroud, R.M. (deposition date: 1997-10-10, release date: 1998-11-11, Last modification date: 2024-06-05) |
Primary citation | Katz, B.A.,Clark, J.M.,Finer-Moore, J.S.,Jenkins, T.E.,Johnson, C.R.,Ross, M.J.,Luong, C.,Moore, W.R.,Stroud, R.M. Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391:608-612, 1998 Cited by PubMed: 9468142DOI: 10.1038/35422 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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