1XRJ

Rapid structure determination of human uridine-cytidine kinase 2 using a conventional laboratory X-ray source and a single samarium derivative

Summary for 1XRJ

• Entry DOI: 10.2210/pdb1xrj/pdb
• Related: 1UDW 1UEI 1UEJ 1UFQ 1UJ2
• Descriptor: Uridine-cytidine kinase 2, MAGNESIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... (5 entities in total)
• Functional Keywords: uridine-cytidine kinase, uck2, nucleoside kinase, oncology, cancer, anti-cancer, rapid phasing, samarium, single-wavelength, anomalous, siras, sad, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 60219.64

Authors

Appleby, T.C.,Larson, G.,Wu, J.Z.,Cheney, I.W.,Hong, Z.,Yao, N. (deposition date: 2004-10-14, release date: 2005-03-15, Last modification date: 2024-02-14)

• Primary citation: Appleby, T.C.,Larson, G.,Cheney, I.W.,Walker, H.,Wu, J.Z.,Zhong, W.,Hong, Z.,Yao, N.; Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative.; Acta Crystallogr.,Sect.D, 61:278-284, 2005; PubMed: 15735337; DOI: 10.1107/S0907444904032937

Experimental method

X-RAY DIFFRACTION (2 Å)