1XR5
Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14
Replaces: 1TEBSummary for 1XR5
Entry DOI | 10.2210/pdb1xr5/pdb |
Related | 1TE8 1TE9 1TEB 1XR6 1XR7 |
Descriptor | Genome polyprotein, SAMARIUM (III) ION (3 entities in total) |
Functional Keywords | rna-dependent rna polymerase, transferase |
Biological source | Human rhinovirus 14 |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 |
Total number of polymer chains | 1 |
Total formula weight | 53289.26 |
Authors | Love, R.A.,Maegley, K.A.,Yu, X.,Ferre, R.A.,Lingardo, L.K.,Diehl, W.,Parge, H.E.,Dragovich, P.S.,Fuhrman, S.A. (deposition date: 2004-10-13, release date: 2004-10-26, Last modification date: 2024-02-14) |
Primary citation | Love, R.A.,Maegley, K.A.,Yu, X.,Ferre, R.A.,Lingardo, L.K.,Diehl, W.,Parge, H.E.,Dragovich, P.S.,Fuhrman, S.A. The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy Structure, 12:1533-1544, 2004 Cited by PubMed: 15296746DOI: 10.1016/j.str.2004.05.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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