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1XQH

Crystal structure of a ternary complex of the methyltransferase SET9 (also known as SET7/9) with a P53 peptide and SAH

1XQH の概要
エントリーDOI10.2210/pdb1xqh/pdb
関連するPDBエントリー1h3i 1o9s
分子名称Histone-lysine N-methyltransferase, H3 lysine-4 specific, 9-mer peptide from tumor protein p53, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
機能のキーワードset9-p53 complex, set-domain, lysine methylation, transferase
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Nucleus: Q8WTS6
Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
タンパク質・核酸の鎖数4
化学式量合計61726.69
構造登録者
主引用文献Chuikov, S.,Kurash, J.K.,Wilson, J.R.,Xiao, B.,Justin, N.,Ivanov, G.S.,McKinney, K.,Tempst, P.,Prives, C.,Gamblin, S.J.,Barlev, N.A.,Reinberg, D.
Regulation of p53 activity through lysine methylation
Nature, 432:353-360, 2004
Cited by
PubMed: 15525938
DOI: 10.1038/nature03117
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (1.75 Å)
構造検証レポート
Validation report summary of 1xqh
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-03-27に公開中

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