1XJW
The Structure of E. coli Aspartate Transcarbamoylase Q137A Mutant in The R-State
Summary for 1XJW
Entry DOI | 10.2210/pdb1xjw/pdb |
Related | 1D09 |
Descriptor | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... (5 entities in total) |
Functional Keywords | allosteric enzyme, polar contacts, electrostatics, small angle x-ray scattering, domain closure, intersubunit interactions, transferase-transferase regulator complex, transferase/transferase regulator |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 103488.42 |
Authors | Stieglitz, K.A.,Alam, N.,Xia, J.,Gourinath, S.,Tsuruta, H.,Kantrowitz, E.R. (deposition date: 2004-09-25, release date: 2005-05-24, Last modification date: 2023-08-23) |
Primary citation | Stieglitz, K.A.,Pastra-Landis, S.C.,Xia, J.,Tsuruta, H.,Kantrowitz, E.R. A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition. J.Mol.Biol., 349:413-423, 2005 Cited by PubMed: 15890205DOI: 10.1016/j.jmb.2005.03.073 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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