1XJW

The Structure of E. coli Aspartate Transcarbamoylase Q137A Mutant in The R-State

1XJW の概要

• エントリーDOI: 10.2210/pdb1xjw/pdb
• 関連するPDBエントリー: 1D09
• 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... (5 entities in total)
• 機能のキーワード: allosteric enzyme, polar contacts, electrostatics, small angle x-ray scattering, domain closure, intersubunit interactions, transferase-transferase regulator complex, transferase/transferase regulator
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 103488.42

構造登録者

Stieglitz, K.A.,Alam, N.,Xia, J.,Gourinath, S.,Tsuruta, H.,Kantrowitz, E.R. (登録日: 2004-09-25, 公開日: 2005-05-24, 最終更新日: 2023-08-23)

• 主引用文献: Stieglitz, K.A.,Pastra-Landis, S.C.,Xia, J.,Tsuruta, H.,Kantrowitz, E.R.; A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition.; J.Mol.Biol., 349:413-423, 2005; PubMed: 15890205; DOI: 10.1016/j.jmb.2005.03.073

実験手法

X-RAY DIFFRACTION (2.71 Å)