1XHL
Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate
Summary for 1XHL
Entry DOI | 10.2210/pdb1xhl/pdb |
Related | 1IPF 1OOE 1SPX |
Descriptor | Short-chain dehydrogenase/reductase family member (5L265), putative Tropinone Reductase-II, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE, ... (4 entities in total) |
Functional Keywords | parallel beta-sheet of seven strands in the order 3214567, three alpha-helices on either side of beta-sheet, seventh alpha-helix on top of beta-sheet, structural genomics, protein structure initiative, scsg, psi, southeast collaboratory for structural genomics, secsg, oxidoreductase |
Biological source | Caenorhabditis elegans |
Total number of polymer chains | 2 |
Total formula weight | 64876.83 |
Authors | Schormann, N.,Karpova, E.,Zhou, J.,Zhang, Y.,Symersky, J.,Bunzel, R.,Huang, W.-Y.,Arabshahi, A.,Qiu, S.,Luan, C.-H.,Gray, R.,Carson, M.,Tsao, J.,Luo, M.,Johnson, D.,Lu, S.,Lin, G.,Luo, D.,Cao, Z.,Li, S.,McKInstry, A.,Shang, Q.,Chen, Y.-J.,Bray, T.,Nagy, L.,DeLucas, L.,Southeast Collaboratory for Structural Genomics (SECSG) (deposition date: 2004-09-20, release date: 2004-09-28, Last modification date: 2023-08-23) |
Primary citation | Schormann, N.,Karpova, E.,Zhou, J.,Zhang, Y.,Symersky, J.,Bunzel, R.,Huang, W.-Y.,Arabshahi, A.,Qiu, S.,Luan, C.-H.,Gray, R.,Carson, M.,Tsao, J.,Luo, M.,Johnson, D.,Lu, S.,Lin, G.,Luo, D.,Cao, Z.,Li, S.,McKInstry, A.,Shang, Q.,Chen, Y.-J.,Bray, T.,Nagy, L.,DeLucas, L. Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate To be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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