1XHB

The Crystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1

Summary for 1XHB

Entry DOI	10.2210/pdb1xhb/pdb
Descriptor	Polypeptide N-acetylgalactosaminyltransferase 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	glycosyltransferase-a (gt-a), transferase
Biological source	Mus musculus (house mouse)
Cellular location	Polypeptide N- acetylgalactosaminyltransferase 1: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Polypeptide N- acetylgalactosaminyltransferase 1 soluble form: Secreted : O08912
Total number of polymer chains	1
Total formula weight	54958.52
Authors	Fritz, T.A.,Hurley, J.H.,Trinh, L.B.,Shiloach, J.,Tabak, L.A. (deposition date: 2004-09-17, release date: 2004-10-26, Last modification date: 2020-07-29)
Primary citation	Fritz, T.A.,Hurley, J.H.,Trinh, L.B.,Shiloach, J.,Tabak, L.A. The beginnings of mucin biosynthesis: The crystal structure of UDP-GalNAc:polypeptide {alpha}-N-acetylgalactosaminyltransferase-T1 Proc.Natl.Acad.Sci.USA, 101:15307-15312, 2004 Cited by PubMed: 15486088 DOI: 10.1073/pnas.0405657101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation