1XDK

Crystal Structure of the RARbeta/RXRalpha Ligand Binding Domain Heterodimer in Complex with 9-cis Retinoic Acid and a Fragment of the TRAP220 Coactivator

1XDK の概要

• エントリーDOI: 10.2210/pdb1xdk/pdb
• 関連するPDBエントリー: 1DKF
• 分子名称: Retinoic acid receptor RXR-alpha, Retinoic acid receptor, beta, Thyroid Receptor Associated Protein 220, ... (5 entities in total)
• 機能のキーワード: nuclear receptor, coactivator, ligand, hormone-growth factor receptor complex, hormone/growth factor receptor
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Nucleus: P28700 P22605
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 128757.06

構造登録者

Pogenberg, V.,Guichou, J.F.,Vivat-Hannah, V.,Kammerer, S.,Perez, E.,Germain, P.,De Lera, A.R.,Gronemeyer, H.,Royer, C.A.,Bourguet, W. (登録日: 2004-09-07, 公開日: 2004-11-09, 最終更新日: 2023-08-23)

• 主引用文献: Pogenberg, V.,Guichou, J.F.,Vivat-Hannah, V.,Kammerer, S.,Perez, E.,Germain, P.,De Lera, A.R.,Gronemeyer, H.,Royer, C.A.,Bourguet, W.; CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES; J.Biol.Chem., 280:1625-1633, 2005; PubMed: 15528208; DOI: 10.1074/jbc.M409302200

実験手法

X-RAY DIFFRACTION (2.9 Å)