1XBA

Crystal structure of apo syk tyrosine kinase domain

1XBA の概要

関連するPDBエントリー1XBB 1XBC
分子名称Tyrosine-protein kinase SYK (2 entities in total)
機能のキーワードspleen typrosine kinase, active conformation, structural genomics, structural genomix, transferase
由来する生物種Homo sapiens (human)
細胞内の位置Cell membrane  P43405
ポリマー鎖数1
分子量合計33884
構造登録者
主引用文献
Atwell, S.,Adams, J.M.,Badger, J.,Buchanan, M.D.,Feil, I.K.,Froning, K.J.,Gao, X.,Hendle, J.,Keegan, K.,Leon, B.C.,Muller-Deickmann, H.J.,Nienaber, V.L.,Noland, B.W.,Post, K.,Rajashankar, K.R.,Ramos, A.,Russell, M.,Burley, S.K.,Buchanan, S.G.
A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase.
J.Biol.Chem., 279:55827-55832, 2004
PubMed: 15507431 (主引用文献が同じPDBエントリー)
DOI: 10.1074/jbc.M409792200
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274604.9%10.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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