1X8T

EPSPS liganded with the (R)-phosphonate analog of the tetrahedral reaction intermediate

Summary for 1X8T

Entry DOI	10.2210/pdb1x8t/pdb
Related	1G6S 1G6T 1MI4 1Q36 1X8R
Descriptor	3-phosphoshikimate 1-carboxyvinyltransferase, [3R-[3A,4A,5B(R*)]]-5-(1-CARBOXY-1-PHOSPHONOETHOXY)-4-HYDROXY-3-(PHOSPHONOOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID, FORMIC ACID, ... (4 entities in total)
Functional Keywords	inside-out alpha-beta barrel, transferase
Biological source	Escherichia coli
Cellular location	Cytoplasm : P0A6D3
Total number of polymer chains	1
Total formula weight	46869.96
Authors	Priestman, M.A.,Healy, M.L.,Becker, A.,Alberg, D.G.,Bartlett, P.A.,Schonbrunn, E. (deposition date: 2004-08-18, release date: 2005-04-19, Last modification date: 2023-08-23)
Primary citation	Priestman, M.A.,Healy, M.L.,Becker, A.,Alberg, D.G.,Bartlett, P.A.,Lushington, G.H.,Schonbrunn, E. Interaction of phosphonate analogues of the tetrahedral reaction intermediate with 5-enolpyruvylshikimate-3-phosphate synthase in atomic detail. Biochemistry, 44:3241-3248, 2005 Cited by PubMed: 15736934 DOI: 10.1021/bi048198d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation