1X0J

Crystal structure analysis of the N-terminal bromodomain of human Brd2

Summary for 1X0J

• Entry DOI: 10.2210/pdb1x0j/pdb
• Descriptor: Bromodomain-containing protein 2, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: alpha-helical domain, bromodomain, binds to acetylated histones, structural genomics, riken structural genomics/proteomics initiative, rsgi, nppsfa, national project on protein structural and functional analyses, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (By similarity): P25440
• Total number of polymer chains: 3
• Total formula weight: 45058.40

Authors

Nakamura, Y.,Umehara, T.,Shirouzu, M.,Padmanabhan, B.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2005-03-23, release date: 2006-06-27, Last modification date: 2011-07-13)

• Primary citation: Nakamura, Y.,Umehara, T.,Shirouzu, M.,Padmanabhan, B.,Yokoyama, S.; Structural basis for acetylated histone H4 recognition by the human Brd2 bromodomain; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)