1X0J
Crystal structure analysis of the N-terminal bromodomain of human Brd2
1X0J の概要
エントリーDOI | 10.2210/pdb1x0j/pdb |
分子名称 | Bromodomain-containing protein 2, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
機能のキーワード | alpha-helical domain, bromodomain, binds to acetylated histones, structural genomics, riken structural genomics/proteomics initiative, rsgi, nppsfa, national project on protein structural and functional analyses, transcription |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Nucleus (By similarity): P25440 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 45058.40 |
構造登録者 | Nakamura, Y.,Umehara, T.,Shirouzu, M.,Padmanabhan, B.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2005-03-23, 公開日: 2006-06-27, 最終更新日: 2011-07-13) |
主引用文献 | Nakamura, Y.,Umehara, T.,Shirouzu, M.,Padmanabhan, B.,Yokoyama, S. Structural basis for acetylated histone H4 recognition by the human Brd2 bromodomain To be Published, |
実験手法 | X-RAY DIFFRACTION (1.8 Å) |
構造検証レポート
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