1X0J

Crystal structure analysis of the N-terminal bromodomain of human Brd2

1X0J の概要

• エントリーDOI: 10.2210/pdb1x0j/pdb
• 分子名称: Bromodomain-containing protein 2, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: alpha-helical domain, bromodomain, binds to acetylated histones, structural genomics, riken structural genomics/proteomics initiative, rsgi, nppsfa, national project on protein structural and functional analyses, transcription
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus (By similarity): P25440
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45058.40

構造登録者

Nakamura, Y.,Umehara, T.,Shirouzu, M.,Padmanabhan, B.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2005-03-23, 公開日: 2006-06-27, 最終更新日: 2011-07-13)

• 主引用文献: Nakamura, Y.,Umehara, T.,Shirouzu, M.,Padmanabhan, B.,Yokoyama, S.; Structural basis for acetylated histone H4 recognition by the human Brd2 bromodomain; To be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)