1WX4

Crystal structure of the oxy-form of the copper-bound Streptomyces castaneoglobisporus tyrosinase complexed with a caddie protein prepared by the addition of dithiothreitol

Summary for 1WX4

Entry DOI	10.2210/pdb1wx4/pdb
Related	1WX2 1WX3 1WX5 1WXC
Descriptor	tyrosinase, MelC, COPPER (II) ION, ... (6 entities in total)
Functional Keywords	tyrosinase, binary complex, type-3 copper, dioxygen, oxidoreductase-metal transport complex, oxidoreductase/metal transport
Biological source	Streptomyces castaneoglobisporus More
Total number of polymer chains	2
Total formula weight	46889.58
Authors	Matoba, Y.,Kumagai, T.,Yamamoto, A.,Yoshitsu, H.,Sugiyama, M. (deposition date: 2005-01-19, release date: 2006-01-31, Last modification date: 2023-10-25)
Primary citation	Matoba, Y.,Kumagai, T.,Yamamoto, A.,Yoshitsu, H.,Sugiyama, M. Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis J.Biol.Chem., 281:8981-8990, 2006 Cited by PubMed: 16436386 DOI: 10.1074/jbc.M509785200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation