1WUR

Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP

1WUR の概要

• エントリーDOI: 10.2210/pdb1wur/pdb
• 関連するPDBエントリー: 1WUQ
• 分子名称: GTP cyclohydrolase I, ZINC ION, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: beta barrel, protein-inhibitor complex, hydrolase, pteridine, tetrahydrobiopterin, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 125799.60

構造登録者

Tanaka, Y.,Nakagawa, N.,Masui, R.,Yokoyama, S.,Kuramitsu, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2004-12-08, 公開日: 2005-07-19, 最終更新日: 2024-03-13)

• 主引用文献: Tanaka, Y.,Nakagawa, N.,Kuramitsu, S.,Yokoyama, S.,Masui, R.; Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative; J.Biochem.(Tokyo), 138:263-275, 2005; PubMed: 16169877; DOI: 10.1093/jb/mvi120

実験手法

X-RAY DIFFRACTION (1.82 Å)