1WUQ
Structure of GTP cyclohydrolase I Complexed with 8-oxo-GTP
Summary for 1WUQ
Entry DOI | 10.2210/pdb1wuq/pdb |
Related | 1WUR |
Descriptor | GTP cyclohydrolase I, ZINC ION, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | beta barrel, protein-inhibitor complex, hydrolase, pteridine, tetrahydrobiopterin, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
Biological source | Thermus thermophilus |
Total number of polymer chains | 5 |
Total formula weight | 125879.60 |
Authors | Tanaka, Y.,Nakagawa, N.,Masui, R.,Yokoyama, S.,Kuramitsu, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2004-12-08, release date: 2005-07-19, Last modification date: 2024-03-13) |
Primary citation | Tanaka, Y.,Nakagawa, N.,Kuramitsu, S.,Yokoyama, S.,Masui, R. Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative J.Biochem.(Tokyo), 138:263-275, 2005 Cited by PubMed: 16169877DOI: 10.1093/jb/mvi120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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