1WT2
Mutant human ABO(H) blood group glycosyltransferase A with bound UDP and inhibitor
Summary for 1WT2
Entry DOI | 10.2210/pdb1wt2/pdb |
Related | 1WSZ 1WT0 1WT1 1WT3 |
Descriptor | Histo-blood group ABO system transferase, alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442 |
Total number of polymer chains | 1 |
Total formula weight | 35638.26 |
Authors | Lee, H.J.,Barry, C.H.,Borisova, S.N.,Seto, N.O.L.,Zheng, R.B.,Blancher, A.,Evans, S.V.,Palcic, M.M. (deposition date: 2004-11-12, release date: 2004-12-07, Last modification date: 2024-03-13) |
Primary citation | Lee, H.J.,Barry, C.H.,Borisova, S.N.,Seto, N.O.L.,Zheng, R.B.,Blancher, A.,Evans, S.V.,Palcic, M.M. Structural basis for the inactivity of human blood group o2 glycosyltransferase J.Biol.Chem., 280:525-529, 2005 Cited by PubMed: 15475562DOI: 10.1074/jbc.M410245200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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