1WT2
Mutant human ABO(H) blood group glycosyltransferase A with bound UDP and inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 292 | 34037.3 | 1 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (human) | ABO(H) blood group glycosyltransferase A |
| 2 | B (B) | alpha-L-fucopyranose-(1-2)-hexyl 3-deoxy-beta-D-galactopyranoside | branched | 394.5 | 1 | In PDB GlyTouCan (G50243CR) | |||
| 3 | C, D, E, F (A) | MERCURY (II) ION | non-polymer | 200.6 | 4 | Chemie (HG) PubChem (26623) | |||
| 4 | G (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (57448939) PubChem (60098857) PubChem (1158) PubChem (6031) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 5 | H (A) | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Met 63 | - | initiating methionine |
| Ser 74 | Pro 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34037.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 394.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1206.5 | |
| All* | Total formula weight | 35638.3 |
