Strucutre of the tetrameric form of Human L-Xylulose Reductase

Summary for 1WNT

DescriptorL-xylulose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords7 stranded parallel beta sheets, 6 alpha helices, rossmann fold, dinucleotide co-enzyme binding motif, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Peripheral membrane protein (By similarity) Q7Z4W1
Total number of polymer chains4
Total molecular weight106737.75
El-Kabbani, O.,Carbone, V.,Darmanin, C.,Ishikura, S.,Hara, A. (deposition date: 2004-08-09, release date: 2005-07-19, Last modification date: 2011-07-13)
Primary citation
El-Kabbani, O.,Carbone, V.,Darmanin, C.,Ishikura, S.,Hara, A.
Structure of the tetrameric form of human L-Xylulose reductase: Probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis
Proteins, 60:424-432, 2005
PubMed: 15906319 (PDB entries with the same primary citation)
DOI: 10.1002/prot.20487
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.213330.5%15.3%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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