1WNT

Structure of the tetrameric form of Human L-Xylulose Reductase

1WNT の概要

• エントリーDOI: 10.2210/pdb1wnt/pdb
• 関連するPDBエントリー: 1PR9
• 分子名称: L-xylulose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• 機能のキーワード: 7 stranded parallel beta sheets, 6 alpha helices, rossmann fold, dinucleotide co-enzyme binding motif, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 106737.75

構造登録者

El-Kabbani, O.,Carbone, V.,Darmanin, C.,Ishikura, S.,Hara, A. (登録日: 2004-08-09, 公開日: 2005-07-19, 最終更新日: 2023-10-25)

• 主引用文献: El-Kabbani, O.,Carbone, V.,Darmanin, C.,Ishikura, S.,Hara, A.; Structure of the tetrameric form of human L-Xylulose reductase: Probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis; Proteins, 60:424-432, 2005; PubMed: 15906319; DOI: 10.1002/prot.20487

実験手法

X-RAY DIFFRACTION (2.3 Å)