1WMA

Crystal structure of human CBR1 in complex with Hydroxy-PP

Summary for 1WMA

Entry DOI	10.2210/pdb1wma/pdb
Descriptor	Carbonyl reductase [NADPH] 1, SULFATE ION, 3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL, ... (7 entities in total)
Functional Keywords	oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P16152
Total number of polymer chains	1
Total formula weight	32994.14
Authors	Rauh, D.,Bateman, R.,Shokat, K.M. (deposition date: 2004-07-06, release date: 2005-04-26, Last modification date: 2024-03-13)
Primary citation	Tanaka, M.,Bateman, R.,Rauh, D.,Vaisberg, E.,Ramachandani, S.,Zhang, C.,Hansen, K.C.,Burlingame, A.L.,Trautman, J.K.,Shokat, K.M.,Adams, C.L. An unbiased cell morphology-based screen for new, biologically active small molecules Plos Biol., 3:128-128, 2005 Cited by PubMed: 15799708 DOI: 10.1371/journal.pbio.0030128 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation