1WDC

SCALLOP MYOSIN REGULATORY DOMAIN

1WDC の概要

• エントリーDOI: 10.2210/pdb1wdc/pdb
• 分子名称: SCALLOP MYOSIN, MAGNESIUM ION, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: myosin, calcium binding protein, muscle protein
• 由来する生物種: Argopecten irradians; 詳細
• 細胞内の位置: Cytoplasm, myofibril: P24733
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 43258.50

構造登録者

Houdusse, A.,Cohen, C. (登録日: 1996-01-19, 公開日: 1996-07-11, 最終更新日: 2024-02-14)

主引用文献

Houdusse, A.,Cohen, C.
Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation.
Structure, 4:21-32, 1996

PubMed Abstract: In contrast to the myosins of vertebrate skeletal muscle, molluscan myosins are regulated molecules whose enzymatic activity is switched on by the direct binding of Ca2+. The head portion (S1) of the molecule consists of a motor domain and a regulatory domain (RD) containing a 'regulatory' and an 'essential' light chain (RLC and ELC, respectively). The structures of scallop myosin RD with bound Ca2+, as well as the S1 fragment of chicken skeletal muscle myosin, have been determined previously to 2.8 A resolution.

PubMed: 8805510
DOI: 10.1016/S0969-2126(96)00154-2

実験手法

X-RAY DIFFRACTION (2 Å)