1W2C
Human Inositol (1,4,5) trisphosphate 3-kinase complexed with Mn2+/AMPPNP/Ins(1,4,5)P3
Summary for 1W2C
Entry DOI | 10.2210/pdb1w2c/pdb |
Related | 1W2D 1W2F |
Descriptor | INOSITOL-TRISPHOSPHATE 3-KINASE A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | inositol phosphate kinase, amppnp, ip3, transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 63101.95 |
Authors | Gonzalez, B.,Schell, M.J.,Irvine, R.F.,Williams, R.L. (deposition date: 2004-07-01, release date: 2004-09-09, Last modification date: 2024-05-08) |
Primary citation | Gonzalez, B.,Schell, M.J.,Letcher, A.J.,Veprintsev, D.B.,Irvine, R.F.,Williams, R.L. Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase Mol.Cell, 15:689-, 2004 Cited by PubMed: 15350214DOI: 10.1016/J.MOLCEL.2004.08.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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