1W1P

Crystal structure of S. marcescens chitinase B in complex with the cyclic dipeptide inhibitor cyclo-(Gly-L-Pro) at 2.1 A resolution

1W1P の概要

• エントリーDOI: 10.2210/pdb1w1p/pdb
• 関連するPDBエントリー: 1E15 1E6N 1E6P 1E6R 1E6Z 1GOI 1GPF 1OGB 1UR8 1UR9 1W1T 1W1V 1W1Y
• 分子名称: CHITINASE B, GLYCEROL, CYCLO-(GLYCINE-L-PROLINE) INHIBITOR, ... (5 entities in total)
• 機能のキーワード: hydrolase, glycoside hydrolase, chitinase, structure-based inhibitor design, cyclic dipeptide
• 由来する生物種: SERRATIA MARCESCENS
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 113762.61

構造登録者

Houston, D.R.,Synstad, B.,Eijsink, V.G.H.,Eggleston, I.,Van Aalten, D.M.F. (登録日: 2004-06-23, 公開日: 2005-01-10, 最終更新日: 2023-12-13)

• 主引用文献: Houston, D.R.,Synstad, B.,Eijsink, V.G.H.,Stark, M.J.,Eggleston, I.,Van Aalten, D.M.F.; Structure-Based Exploration of Cyclic Dipeptide Chitinase Inhibitors; J.Med.Chem., 47:5713-, 2004; PubMed: 15509170; DOI: 10.1021/JM049940A

実験手法

X-RAY DIFFRACTION (2.1 Å)