1VYJ

Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design

Summary for 1VYJ

Entry DOI	10.2210/pdb1vyj/pdb
Related	1AXC 1U76 1U7B 1VYM 1W60
Descriptor	PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK (3 entities in total)
Functional Keywords	dna, replication, processivity, oncogene, dna-binding protein, dna replication, dna-binding systemic lupus erythematosus, dna binding protein
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	12
Total formula weight	184224.11
Authors	Kontopidis, G.,Wu, S.,Zheleva, D.,Taylor, P.,Mcinnes, C.,Lane, D.,Fischer, P.,Walkinshaw, M.D. (deposition date: 2004-04-30, release date: 2005-01-13, Last modification date: 2023-12-13)
Primary citation	Kontopidis, G.,Wu, S.,Zheleva, D.,Taylor, P.,Mcinnes, C.,Lane, D.,Fischer, P.,Walkinshaw, M.D. Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102:1871-, 2005 Cited by PubMed: 15681588 DOI: 10.1073/PNAS.0406540102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation