1VYJ
Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design
Summary for 1VYJ
Entry DOI | 10.2210/pdb1vyj/pdb |
Related | 1AXC 1U76 1U7B 1VYM 1W60 |
Descriptor | PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK (3 entities in total) |
Functional Keywords | dna, replication, processivity, oncogene, dna-binding protein, dna replication, dna-binding systemic lupus erythematosus, dna binding protein |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 12 |
Total formula weight | 184224.11 |
Authors | Kontopidis, G.,Wu, S.,Zheleva, D.,Taylor, P.,Mcinnes, C.,Lane, D.,Fischer, P.,Walkinshaw, M.D. (deposition date: 2004-04-30, release date: 2005-01-13, Last modification date: 2023-12-13) |
Primary citation | Kontopidis, G.,Wu, S.,Zheleva, D.,Taylor, P.,Mcinnes, C.,Lane, D.,Fischer, P.,Walkinshaw, M.D. Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102:1871-, 2005 Cited by PubMed: 15681588DOI: 10.1073/PNAS.0406540102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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